Factors Associated with Complex Regional Pain Syndrome in Patients with Surgically Treated Distal Radius Fracture
-
Yousef Fallah
,
Mohsen Rezaei
,
Ramin Shayan-Moghadam
,
Salar Baghbani
,
Sahar Zafarmandi
,
Ehsan Mahmoudi
Abstract
Background: Complex regional pain syndrome (CRPS) is an important common complication after surgical treatment for distal radius fracture. Recognition of the related factors is important to reduce the burden of the problem. Herein, the contributing factors for CRPS after distal radius fracture surgery are studied.
Methods: In this cross-sectional comparative study, 250 patients admitted to the orthopedics ward in Sina Hospital in Tehran, Iran, from 2017 to 2020, were enrolled. The contributing factors for CRPS after distal radius fracture surgery were determined in them. Results: The CRPS was seen in 17 cases (6.8%). 9 percent of male and 1.9 percent of female patients were diagnosed with CRPS. This showed a significant difference in the Fisher test (P = 0.028). The mean pain severity by Visual Analogue Scale (VAS) was higher in CRPS cases, that showed a significant difference by the Mann-Whitney test (P = 0.001).
Conclusion: According to the obtained results, it may be concluded that CRPS was seen in seven percent of patients under surgery for distal radius fracture and was related to the male gender and higher pain severity.
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16. Zale C, Hansen J, Ryan P. Complex regional pain syndrome: Current practice management and referral trends in a closed healthcare system. Osteology. 2021; 1(1):39-47. doi: 10.3390/osteology1010004.
2. Tolva VS, Kahlberg A, Bertoglio L, Trimarchi S, Miloro R, Casana R, et al. Complex regional pain syndrome with aortic distress after thoracic endovascular aortic repair and false lumen exclusion with "Candy Plug" technique. Aorta (Stamford). 2021;9(3):113-5. doi: 10.1055/s-0041-1730007. [PubMed: 34644804]. [PubMed Central: PMC8598316].
3. Sharma A, Agarwal S, Broatch J, Raja SN. A web-based cross-sectional epidemiological survey of complex regional pain syndrome. Reg Anesth Pain Med. 2009;34(2):110-5. doi: 10.1097/AAP.0b013e3181958f90. [PubMed: 19282709].
4. Lee J, Lim YH, Hong SJ, Jeong JH, Choi HR, Park SK, et al. Multicenter survey of symptoms, work life, economic status, and quality of life of complex regional pain syndrome patients. Korean J Pain. 2021;34(3):288-303. doi: 10.3344/kjp.2021.34.3.288. [PubMed: 34193635]. [PubMed Central: PMC8255153].
5. Baron R. Mechanistic and clinical aspects of complex regional pain syndrome (CRPS). Novartis Found Symp. 2004;261:220-33. [PubMed: 15469053].
6. Harden RN, Bruehl S, Stanton-Hicks M, Wilson PR. Proposed new diagnostic criteria for complex regional pain syndrome. Pain Med. 2007;8(4):326-31. doi: 10.1111/j.1526-4637.2006.00169.x. [PubMed: 17610454].
7. Eide PK, Jorum E, Stubhaug A, Bremnes J, Breivik H. Relief of post-herpetic neuralgia with the N-methyl-D-aspartic acid receptor antagonist ketamine: a double-blind, cross-over comparison with morphine and placebo. Pain. 1994;58(3): 347-54. doi: 10.1016/0304-3959(94)90129-5. [PubMed: 7838584].
8. Treede RD. The International Association for the Study of Pain definition of pain: as valid in 2018 as in 1979, but in need of regularly updated footnotes. Pain Rep. 2018;3(2):e643. doi:
10.1097/PR9.0000000000000643.[PubMed:29756089].
[PubMed Central: PMC5902252].
9. St John SE. Advances in understanding nociception and neuropathic pain. J Neurol. 2018;265(2):231-8. doi: 10.1007/s00415-017-8641-6. [PubMed: 29032407]. [PubMed Central: PMC5808094].
10. Sneddon LU. Comparative Physiology of Nociception and Pain.
Physiology (Bethesda). 2018;33(1):63-73. doi:
10.1152/physiol.00022.2017. [PubMed: 29212893].
11. Zlatkovic-Svenda MI, Leitner C, Lazovic B, Petrovic DM. Complex Regional Pain Syndrome (Sudeck Atrophy) prevention possibility and accelerated recovery in patients with distal radius at the typical site fracture using polarized, polychromatic light therapy. Photobiomodul Photomed Laser Surg. 2019;37(4):233-9. doi: 10.1089/photob.2018.4544. [PubMed: 31050956].
12. Mertens MG, Hermans L, Crombez G, Goudman L, Calders P, Van OJ, et al. Comparison of five conditioned pain modulation paradigms and influencing personal factors in healthy adults. Eur J Pain. 2021;25(1):243-56. doi: 10.1002/ejp.1665. [PubMed: 32965727].
13. Jo YH, Kim K, Lee BG, Kim JH, Lee CH, Lee KH. Incidence of and Risk Factors for complex regional pain syndrome type 1 after surgery for distal radius fractures: A population-based study. Sci Rep. 2019;9(1):4871. doi: 10.1038/s41598-019-41152-x. [PubMed: 30890732]. [PubMed Central: PMC6425010].
14. Ortiz-Romero J, Bermudez-Soto I, Torres-Gonzalez R, Espinoza-Choque F, Zazueta-Hernandez JA, Perez-Atanasio JM. Factors associated with complex regional pain syndrome in surgically treated distal radius fracture. Acta Ortop Bras. 2017;25(5):194-6. doi: 10.1590/1413-785220172505165544. [PubMed: 29081703]. [PubMed Central: PMC5608737].
15. Roh YH, Lee BK, Noh JH, Baek JR, Oh JH, Gong HS, et al. Factors associated with complex regional pain syndrome type I in patients with surgically treated distal radius fracture. Arch Orthop Trauma Surg. 2014;134(12):1775-81. doi: 10.1007/s00402-014-2094-5. [PubMed: 25311113].
16. Zale C, Hansen J, Ryan P. Complex regional pain syndrome: Current practice management and referral trends in a closed healthcare system. Osteology. 2021; 1(1):39-47. doi: 10.3390/osteology1010004.
| Files | ||
| Issue | Vol 9, No 2 (2023) | |
| Section | Research Articles | |
| DOI | https://doi.org/10.18502/jost.v9i2.12623 | |
| Keywords | ||
| Risk Factor Complex Regional Pain Syndrome Wrist Fractures | ||
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How to Cite
1.
Fallah Y, Rezaei M, Shayan-Moghadam R, Baghbani S, Zafarmandi S, Mahmoudi E. Factors Associated with Complex Regional Pain Syndrome in Patients with Surgically Treated Distal Radius Fracture. J Orthop Spine Trauma. 2023;9(2):62-4.
