Tehran University of Medical Sciences Journal of Orthopedic and Spine Trauma 2538-2330 9 2 2023 08 03 62 4 Yousef Fallah Department of Orthopedic Surgery, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran Mohsen Rezaei Department of Orthopedic Surgery, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran Ramin Shayan-Moghadam Department of Orthopedic and Trauma Surgery, Shariati Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Salar Baghbani Department of Orthopaedic surgery, Sina hospital, Tehran University of Medical Sciences , Tehran , Iran Sahar Zafarmandi School of Medicine, Tehran University of Medical Science, Tehran, Iran Ehsan Mahmoudi Department of Orthopaedic surgery, Shariati hospital, Tehran University of Medical Sciences , Tehran , Iran 2022 05 05 2022 12 07 Background: Complex regional pain syndrome (CRPS) is an important common complication after surgical treatment for distal radius fracture. Recognition of the related factors is important to reduce the burden of the problem. Herein, the contributing factors for CRPS after distal radius fracture surgery are studied. Methods: In this cross-sectional comparative study, 250 patients admitted to the orthopedics ward in Sina Hospital in Tehran, Iran, from 2017 to 2020, were enrolled. The contributing factors for CRPS after distal radius fracture surgery were determined in them. Results: The CRPS was seen in 17 cases (6.8%). 9 percent of male and 1.9 percent of female patients were diagnosed with CRPS. This showed a significant difference in the Fisher test (P = 0.028). The mean pain severity by Visual Analogue Scale (VAS) was higher in CRPS cases, that showed a significant difference by the Mann-Whitney test (P = 0.001). Conclusion: According to the obtained results, it may be concluded that CRPS was seen in seven percent of patients under surgery for distal radius fracture and was related to the male gender and higher pain severity https://jost.tums.ac.ir/index.php/jost/article/view/390 https://jost.tums.ac.ir/index.php/jost/article/download/390/314