Tehran University of Medical Sciences Journal of Orthopedic and Spine Trauma 2538-2330 3 3 2017 09 15 76 76 Karim Pisoudeh Shafa Hospital, Iran University of Medical Sciences, Tehran, Iran SM Javad Mortazavi Joint Reconstruction Research Center, Imam Hospital, Tehran University of Medical Sciences, Tehran, Iran Reza Shahriar Kamrani Joint Reconstruction Research Center, Imam Hospital, Tehran University of Medical Sciences, Tehran, Iran Seyyed Hamidreza Seyyedhosseinzadeh Akhtar Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran Mansour Abolghasemian Shafa Hospital, Iran University of Medical Sciences, Tehran, Iran 2019 07 18 Orthopedic trauma is an area of significant controversy regarding indications and type of thromboprophylaxis. In 2014, the Iranian Orthopedic Association (IOA) organized a committee to review the available data to extract a national guideline to assist the orthopedic surgeons in decision making regarding the need and type of thromboprophylaxis for patients with orthopedic trauma. We found almost 12500 articles in regards to DVT and thromboembolism from PubMed and orthopedic journals from January 2004 to January 2017. We included only the articles related to orthopedic trauma patients (684 articles); then, we selected case control cohort and prospective studies (73 articles). Herein, we present a summary of the review. https://jost.tums.ac.ir/index.php/jost/article/view/76 https://jost.tums.ac.ir/index.php/jost/article/download/76/76