Tehran University of Medical Sciences Journal of Orthopedic and Spine Trauma 2538-2330 11 1 2025 03 02 23 26 EN Hindalahally Karthik Junior Resident, H.B.T Medical College and Dr R.N. Cooper Hospital Bhaktivedanta Swami Road Mumbai Juhu Mumbai, Maharashtra Tushar Ubale Associate Professor, H.B.T Medical College and Dr R.N. Cooper Hospital Bhaktivedanta Swami Road Mumbai Juhu Mumbai, Maharashtra Mahesh Shinde Senior resident, H.B.T Medical college and Dr R.N. Cooper hospital Bhaktivedanta Swami Road Mumbai Juhu Mumbai, Maharashtra Mihir Patel Associate Professor, H.B.T Medical College and Dr R.N. Cooper Hospital Bhaktivedanta Swami Road Mumbai Juhu Mumbai, Maharashtra Atharva Sharma Junior Resident, H.B.T Medical College and Dr R.N. Cooper Hospital Bhaktivedanta Swami Road Mumbai Juhu Mumbai, Maharashtra Kshitij Sarwey Junior resident H.B.T Medical College and Dr R.N. Cooper Hospital Bhaktivedanta Swami Road Mumbai Juhu Mumbai, Maharashtra Vinod Bhuktar Junior Resident, H.B.T Medical College and Dr R.N. Cooper Hospital Bhaktivedanta Swami Road Mumbai Juhu Mumbai, Maharashtra Sanket Jethliya Junior resident H.B.T Medical College and Dr R.N. Cooper Hospital Bhaktivedanta Swami Road Mumbai Juhu Mumbai, Maharashtra Naman Khurana Medical Student, H.B.T Medical college and Dr R.N. Cooper hospital Bhaktivedanta Swami Road Mumbai Juhu Mumbai, Maharashtra Tej Bopardikar Medical Student, H.B.T Medical College and Dr R.N. Cooper Hospital Bhaktivedanta Swami Road Mumbai Juhu Mumbai, Maharashtra Vedita Bapat Medical Student, H.B.T Medical College and Dr R.N. Cooper Hospital Bhaktivedanta Swami Road Mumbai Juhu Mumbai, Maharashtra Manni Dwivedi Medical Student, H.B.T Medical College and Dr R.N. Cooper Hospital Bhaktivedanta Swami Road Mumbai Juhu Mumbai, Maharashtra 2024 11 26 2025 02 24 Background: Spondylolisthesis is characterized by the anterior or posterior displacement of a vertebra relative to the adjacent inferior vertebra. Patients with grade I-IV spondylolisthesis are initially treated by conservative measures, but surgical intervention becomes necessary for those with persistent symptoms. Surgical options range from pars repair in spondylosis to various fusion techniques, including instrumented reduction and fusion, or instrumented in situ fusion. The study aimed to evaluate the functional outcomes of surgical instrumentation in low-grade spondylolisthesis. Methods: This retrospective study included 30 patients with low-grade spondylolisthesis who underwent surgical instrumentation. Pain and functional outcomes were evaluated using the Visual Analog Scale (VAS) and modified Oswestry Disability Index (ODI) at baseline and follow-up intervals. Results: The baseline mean VAS score of 7.4 improved significantly at 6, 12, and 24 months (P < 0.01). The baseline mean ODI score of 66.8 also improved significantly at these intervals, with a final mean score of 12.51 at 24 months. Complications occurred in 3 patients, including neurological deficits and bone graft retropulsion. Conclusion: Surgical instrumentation leads to significant improvements in pain and function in patients with low-grade spondylolisthesis, offering excellent outcomes for those unresponsive to conservative treatment. https://jost.tums.ac.ir/index.php/jost/article/view/638 https://jost.tums.ac.ir/index.php/jost/article/download/638/400