Tehran University of Medical Sciences Journal of Orthopedic and Spine Trauma 2538-2330 11 2 2025 06 15 77 80 Reza Zandi Associate professor of Department of Orthopedic Surgery, Musculoskeletal Research Center, Taleghani Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran Shahin Talebi Associate professor of Department of Orthopedic Surgery, Musculoskeletal Research Center, Taleghani Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran Farnam Behroo Intern, Shahid Beheshti university of medical science, Tehran, Iran Saeed Nodehi Resident, Musculoskeletal Research Center, Taleghani Hospital, Shahid Beheshti university of medical science, Tehran, Iran Akbar Ehsani Department of Orthopedic Surgery, Faculty of Medicine, Shahid Beheshti University, Tehran, Iran 2024 09 24 2025 04 26 Background: Heterotopic ossification (HO) around the hip joint is correlated with a dramatic reduction in hip range of motion (ROM) and quality of life (QOL). Case Report: We report on a 45-year-old man with a massive right hip HO with intensive reduction in his right hip ROM. He underwent surgical resection via Smith-Petersen approach by an experienced hip surgeon, as well as a vascular surgeon. Neurovascular bundle was explored and protected. The mass was excised as much as possible. The ROM increased instantly to near full. After surgery, we used indomethacin in order to hinder the HO relapse. Conclusion: The surgical resection of hip HO is a feasible treatment option; however, it is challenging. https://jost.tums.ac.ir/index.php/jost/article/view/627 https://jost.tums.ac.ir/index.php/jost/article/download/627/413