Tehran University of Medical Sciences Journal of Orthopedic and Spine Trauma 2538-2330 11 1 2025 03 02 42 4 Amit Awachat MS ORTHOPAEDICS. Fortis Hospital, Mulund, Mumbai, India. Kumar Shetty Consultant Spine Surgeon, Fortis Hospital, Mulund, Mumbai, India Vikas Gupte Senior Consultant Spine Surgeon, Fortis Hospital, Mulund, Mumbai, India Shrinivas Prabhu Assistant Professor, MGM Institute of Medical Science, Kamothe, Navi Mumbai, India 2024 06 11 2025 02 24 Background: Vertebral hemangiomas are the most common primary vertebral tumor of the spine, usually with vascular origin (capillary and venous malformations), and are detected incidentally in most cases. The occurrence of vertebral hemangiomas is more common in women than men and is more symptomatic in the fourth decade of life. The exact etiology is not well understood. An increase in daily living activity leads to vertebral hemangioma becoming painful. The proliferation of hemangiomas causes erosion of bone and, in some cases, causes encroachment into the spinal canal. Case Report: We present a case of a 37-year-old man with gradually progressive paraplegia and a D2 level infiltrative mass causing compression on the spinal cord. Conclusion: A patient with vertebral hemangioma with spinal cord compression, if diagnosed correctly and treated early with surgical intervention, results in a good prognostic outcome. https://jost.tums.ac.ir/index.php/jost/article/view/599 https://jost.tums.ac.ir/index.php/jost/article/download/599/405