Tehran University of Medical Sciences Journal of Orthopedic and Spine Trauma 2538-2330 10 4 2024 12 30 170 3 EN Alireza Moharrami Joint Reconstruction Research Center, Tehran University of Medical Sciences Mohammad Mirahmadi Eraghi Joint Reconstruction Research Center, Tehran University of Medical Sciences Shahabaldin Beheshti Fard Joint Reconstruction Research Center, Tehran University of Medical Sciences Ali Asadifar Resident of Radiology, Department of Radiology, Afzalipour Faculity of Medicine, Kerman University of Medical Scineces, Kerman, Iran, Ali Salehi Resident of Radiology, Imam Hosein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Sadulla Sharifpour Orthopedic Surgeon, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran SM Javad Mortazavi Joint Reconstruction Research Center, Tehran University of Medical Sciences 2023 06 06 2024 12 21 Low back pain (LBP) is a significant issue in both clinical and public health settings, resulting in high healthcare and social costs. While knee joint pain is more prevalent than hip joint pain, standing posture is influenced not only by spinal alignment but also by hip and knee joint alignment. The knee and spine are interconnected anatomically, and degenerative changes in one area could often cause discomfort in the entire axis, leading to what is known as "knee-spine syndrome". LBP is a common condition associated with knee pain and can significantly affect the results of total knee arthroplasty (TKA). Surgeons need to consider knee-spine syndrome before any surgical intervention in patients with knee or back pain and explain it to the patients before the surgery. https://jost.tums.ac.ir/index.php/jost/article/view/503 https://jost.tums.ac.ir/index.php/jost/article/download/503/392