Tehran University of Medical Sciences Journal of Orthopedic and Spine Trauma 2538-2330 7 4 2022 04 04 127 133 Adel Ebrahimpour Department of Orthopedics, Shohada Tajrish Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran Mohammadreza Chehrassan Bone and Joint Reconstruction Research Center, Shafa Hospital, Iran University of Medical Sciences, Tehran, Iran Amir Human Hoveidaei Sports Medicine Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran Meisam Jafari Kafiabadi Department of Orthopedics, Shohada Tajrish Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran Mehrdad Sadighi Department of Orthopedics, Shohada Tajrish Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran Alireza Manafi Rasi Department of Orthopedic Surgery, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran Morteza Sanei Taheri Department of Radiology, Shohada Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran Alireza Fatemi Men’s Health and Reproductive Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran SM Javad Mortazavi Joint Reconstruction Research Center, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran 2021 07 26 2022 02 26 Background: COVID-19 is spreading rapidly and potentially affects every person, including fracture patients. This study was conducted with the aim to evaluate our primary months’ experience of surgical treatment of fractures in COVID-19 infected patients in order to assist in better decision-making in the next waves of the infection.   Methods: In this cross-sectional study, 15 patients with orthopedic trauma and COVID-19 infection were included from 2 trauma centers during February and March 2020.   Results: Most of the patients were younger than 40 year of age. The most common COVID-19 related symptom at presentation was malaise, and a hypoxia rate of 85.7% was detected among the patients. Two-thirds of the fractures were in the lower extremities. One patient expired, but all others were discharged with no follow-up complications.   Conclusion: Surgical management of fractures in COVID-19 patients is inevitable. To achieve this, sensitive screening techniques and standard protection measures are essential. https://jost.tums.ac.ir/index.php/jost/article/view/299 https://jost.tums.ac.ir/index.php/jost/article/download/299/242