<?xml version="1.0"?>
<Articles JournalTitle="Journal of Orthopedic and Spine Trauma">
  <Article>
    <Journal>
      <PublisherName>Tehran University of Medical Sciences</PublisherName>
      <JournalTitle>Journal of Orthopedic and Spine Trauma</JournalTitle>
      <Issn>2538-2330</Issn>
      <Volume>7</Volume>
      <Issue>3</Issue>
      <PubDate PubStatus="epublish">
        <Year>2022</Year>
        <Month>03</Month>
        <Day>05</Day>
      </PubDate>
    </Journal>
    <title locale="en_US">A Web-Based Dynamic Nomogram to Calculate the Risk of Nonhealing after Femoral Neck Fracture Fixation among Young Adults: Bench to Bedside Translational Research</title>
    <FirstPage>85</FirstPage>
    <LastPage>94</LastPage>
    <AuthorList>
      <Author>
        <FirstName>Babak</FirstName>
        <LastName>Siavashi</LastName>
        <affiliation locale="en_US">Department of Orthopedics, Sina Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Mohammad</FirstName>
        <LastName>Heshmati</LastName>
        <affiliation locale="en_US">Department of Orthopedics, Sina Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Mohammad Reza</FirstName>
        <LastName>Golbakhsh</LastName>
        <affiliation locale="en_US">Department of Orthopedics, Sina Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Seyyed Hossein</FirstName>
        <LastName>Shafiei</LastName>
        <affiliation locale="en_US">Assistant Professor, Department of Orthopedics, Sina Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Farhad</FirstName>
        <LastName>Mahdavi</LastName>
        <affiliation locale="en_US">Department of Orthopedics, Sina Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Mohammadreza</FirstName>
        <LastName>Sadeghi</LastName>
        <affiliation locale="en_US">Department of Orthopedics, Sina Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Yegane</FirstName>
        <LastName>Yousefifar</LastName>
        <affiliation locale="en_US">Department of Orthopedics, Sina Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Salar</FirstName>
        <LastName>Baghbani</LastName>
        <affiliation locale="en_US">Department of Orthopedics, Sina Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Mohammadreza</FirstName>
        <LastName>Bozorgmanesh</LastName>
        <affiliation locale="en_US">Department of Orthopedics, Vali-e-Asr Hospital, School of Medicine, Arak University of Medical Sciences, Arak, Iran</affiliation>
      </Author>
    </AuthorList>
    <History>
      <PubDate PubStatus="received">
        <Year>2021</Year>
        <Month>06</Month>
        <Day>29</Day>
      </PubDate>
      <PubDate PubStatus="accepted">
        <Year>2021</Year>
        <Month>08</Month>
        <Day>31</Day>
      </PubDate>
    </History>
    <abstract locale="en_US">Background: The aim of this study was to develop a prognostic model to identify a subgroup of high-risk patients for non-healing after femoral neck fracture fixation among young adults. The model was implemented by presenting graphically as a nomogram that could be easily used in every day clinical cases.
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Methods: Data on a total of 129 patients were included in the current study. The mean [standard deviation (SD)] age of the participants was 42 (13) years and 28% of the patients were women. Harrell&#x2019;s C statistic was used as a measure of discrimination predictive power. We calculated the Nam-D&#x2019;Agostino &#x3C7;2 to examine calibration for prediction models.
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Results: Approximately, 83% of fractures united uneventfully, with avascular necrosis (AVN), fixation nonhealing, non-union, infection, arthroplasty, and death being observed. Body mass index (BMI) and head acetabular trabecular angle (HATA) were inversely associated with the risk of all-cause nonhealing. The final model showed excellent discriminatory power [Harrell&#x2019;s C statistic: 0.820, 95% confidence interval (CI) (0.680-0.960)] and it was well-calibrated [Nam-D&#x2019;Agostino &#x3C7;2: 10.1, (P = 0.3456)]. A
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nomogram developed by incorporating significant predictors modelled without discretizing continuous variables.
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Conclusion: Using readily available clinical and radiological data, we developed a parsimonious, simple, accurate yardstick to measure the 5-year risk of nonhealing after femoral neck fractures among young adults. In order to add ease-of-use and to promote its integration into clinical practice, the prognostic model was demonstrated visually as a statistic nomogram.</abstract>
    <web_url>https://jost.tums.ac.ir/index.php/jost/article/view/295</web_url>
    <pdf_url>https://jost.tums.ac.ir/index.php/jost/article/download/295/236</pdf_url>
  </Article>
</Articles>
