Tehran University of Medical Sciences Journal of Orthopedic and Spine Trauma 2538-2330 6 2 2021 01 18 43 7 Seyyed Hossein Shafiei Assistant Professor, Department of Orthopedic Surgery, Sina Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Salar baghbani Sina Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Mohsen Nosrati Sina Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Babak Siavashi Department of Orthopedic Surgery, Sina Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Mohammad Reza Golbakhsh Department of Orthopedic Surgery, Sina Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran 2020 08 11 2020 11 15   Background: During the outbreak of the novel coronavirus disease 2019 (COVID-19), Sina Hospital in Tehran, Iran, dedicated a majority of its facilities and workforce to fight this crisis. Meanwhile, our academic trauma center continued to admit emergency trauma patients.   Case Report: In this case series, we tried to discuss five previously healthy trauma patients who underwent orthopedic surgery and were diagnosed with COVID-19 later. Also, we described our detailed protocol for the management of orthopedic patients during the pandemic. Conclusion: During COVID-19 time, we continued to provide our best service to the trauma patients while keeping our personnel as far as possible from direct contact with the patients until it was necessary. https://jost.tums.ac.ir/index.php/jost/article/view/208 https://jost.tums.ac.ir/index.php/jost/article/download/208/179