Pseudomyxoma peritonei lesion of the thoracic spine
A Case Report and literature review.
-
Hieu Kim Huynh
,
Maxime Lacroix
,
Pierre Guigui
,
Emmanuelle Ferrero
,
Tchao Meatchi
,
Marc Khalifé
Abstract
Case description:
We report here the case of a 64-year-old male presenting pathological fractures of T6 and T7 due to pseudomyxoma peritonei extension to the pleural cavity and thoracic spine. He presented interscapular pain with mild spinal cord compression symptoms. He was treated by achieving T5-T8 laminectomy, T2-T10 pedicle fixation, and T6-T7 vertebrectomy. The postoperative course was uneventful apart from a pulmonary embolism with favorable evolution under anticoagulants.
Conclusion: Pseudomyxoma peritonei is a rare condition, with no previously described location in the spine. Here is described the case of a PMP extension to the thorax then the spine, treated with two-level vertebrectomy, laminectomy, and posterior fusion.
1. Yu B., & Raj M. S. (2022). Pseudomyxoma Peritonei
2. O’Connell J. T., Tomlinson J. S., Roberts A. A., McGonigle K. F., & Barsky S. H. (2002). Pseudomyxoma peritonei is a disease of MUC2-expressing goblet cells. The American journal of pathology, 161(2), 551-64. https://doi.org/10.1016/S0002-9440(10)64211-3
3. Csanyi-Bastien M., Blanchard F., Lamy A., & Sabourin J.-C. (2021). A case of Pseudomyxoma Peritonei of an unexpected origin. Diagnostic pathology, 16(1), 119. https://doi.org/10.1186/s13000-021-01179-z
4. Moran B. J., & Cecil T. D. (2003). The etiology, clinical presentation, and management of pseudomyxoma peritonei. Surgical oncology clinics of North America, 12(3), 585-603. https://doi.org/10.1016/s1055-3207(03)00026-7
5. Mittal R., Chandramohan A., & Moran B. (2017). Pseudomyxoma peritonei: natural history and treatment. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 33(5), 511-519. https://doi.org/10.1080/02656736.2017.1310938
6. Esquivel J., & Sugarbaker P. H. (2000). Clinical presentation of the Pseudomyxoma peritonei syndrome. The British journal of surgery, 87(10), 1414-8. https://doi.org/10.1046/j.1365-2168.2000.01553.x
7. Carr N. J., Finch J., Ilesley I. C., Chandrakumaran K., Mohamed F., Mirnezami A., et al. (2012). Pathology and prognosis in pseudomyxoma peritonei: a review of 274 cases. Journal of clinical pathology, 65(10), 919-23. https://doi.org/10.1136/jclinpath-2012-200843
8. Khalifé M., Guigui P., Hoffmann E., & Ferrero E. (2020). Techniques d ’ ostéotomie vertébrale. 0(20), 1-19. https://doi.org/10.1016/S0246-0467(20)42625-X
9. Carr N. J., Cecil T. D., Mohamed F., Sobin L. H., Sugarbaker P. H., González-Moreno S., et al. (2016). A Consensus for Classification and Pathologic Reporting of Pseudomyxoma Peritonei and Associated Appendiceal Neoplasia: The Results of the Peritoneal Surface Oncology Group International (PSOGI) Modified Delphi Process. The American journal of surgical pathology, 40(1), 14-26. https://doi.org/10.1097/PAS.0000000000000535
10. Smeenk R. M., van Velthuysen M. L. F., Verwaal V. J., & Zoetmulder F. A. N. (2008). Appendiceal neoplasms and pseudomyxoma peritonei: a population based study. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 34(2), 196-201. https://doi.org/10.1016/j.ejso.2007.04.002
11. Belhamidi M. S., Zorkani Y., Krimou H., Kaoukabi A., Menfaa M., Sakit F., et al. (2019). [Pseudomyxoma peritonei (PMP) secondary to mucinous carcinoma of the ovary: a case study]. The Pan African medical journal, 33, 283. https://doi.org/10.11604/pamj.2019.33.283.17203
12. Ning S., Yang Y., Wang C., & Luo F. (2019). Pseudomyxoma peritonei induced by low-grade appendiceal mucinous neoplasm accompanied by rectal cancer: a case report and literature review. BMC surgery, 19(1), 42. https://doi.org/10.1186/s12893-019-0508-6
13. Prabhu R. M., Koshire S. R., & Khandelwal R. C. S. (2021). A Rare Case of Psoas Abscess Secondary to Mucinous Adenocarcinoma of the Appendix: A Case Report. Journal of orthopaedic case reports, 11(8), 1-5. https://doi.org/10.13107/jocr.2021.v11.i08.2340
14. Ghosh R. K., Somasundaram M., Ravakhah K., & Hassan C. (2016). Pseudomyxoma peritonei with intrathoracic extension: a rare disease with rarer presentation from low-grade mucinous adenocarcinoma of the appendix. BMJ case reports, 2016. https://doi.org/10.1136/bcr-2015-211076
15. Youssef H., Newman C., Chandrakumaran K., Mohamed F., Cecil T. D., & Moran B. J. (2011). Operative findings, early complications, and long-term survival in 456 patients with pseudomyxoma peritonei syndrome of appendiceal origin. Diseases of the colon and rectum, 54(3), 293-9. https://doi.org/10.1007/DCR.0b013e318202f026
16. McBride K., McFadden D., & Osler T. (2013). Improved survival of patients with pseudomyxoma peritonei receiving intraperitoneal chemotherapy with cytoreductive surgery: a systematic review and meta-analysis. The Journal of surgical research, 183(1), 246-52. https://doi.org/10.1016/j.jss.2012.12.040
17. Baratti D., Kusamura S., Guaglio M., Milione M., Pietrantonio F., Cavalleri T., et al. (2022). Relapse of Pseudomyxoma Peritonei After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: Pattern of Failure, Clinical Management and Outcomes. Annals of surgical oncology. https://doi.org/10.1245/s10434-022-12367-6
18. Proesmans V., Vandaele T., Van Slambrouck J., Wolthuis A., D Hoore A., Dekervel J., et al. (2022). Pleural decortication and hyperthermic intrathoracic chemotherapy for pseudomyxoma. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 39(1), 1153-1157. https://doi.org/10.1080/02656736.2022.2104938
19. Pestieau S. R., Esquivel J., & Sugarbaker P. H. (2000). Pleural extension of mucinous tumor in patients with pseudomyxoma peritonei syndrome. Annals of surgical oncology, 7(3), 199-203. https://doi.org/10.1007/BF02523654
20. Sugarbaker P. H., Chang D., & Stuart O. A. (2012). Hyperthermic intraoperative thoracoabdominal chemotherapy. Gastroenterology research and practice, 2012, 623417. https://doi.org/10.1155/2012/623417
21. Yahanda A. T., Buchowski J. M., & Wegner A. M. (2019). Treatment, complications, and outcomes of metastatic disease of the spine: from Patchell to PROMIS. Annals of translational medicine, 7(10), 216. https://doi.org/10.21037/atm.2019.04.83
22. Lau D., Deviren V., & Ames C. P. (2019). The impact of surgeon experience on perioperative complications and operative measures following thoracolumbar 3-column osteotomy for adult spinal deformity: overcoming the learning curve. Journal of neurosurgery. Spine, 32(2), 207-220. https://doi.org/10.3171/2019.7.SPINE19656
2. O’Connell J. T., Tomlinson J. S., Roberts A. A., McGonigle K. F., & Barsky S. H. (2002). Pseudomyxoma peritonei is a disease of MUC2-expressing goblet cells. The American journal of pathology, 161(2), 551-64. https://doi.org/10.1016/S0002-9440(10)64211-3
3. Csanyi-Bastien M., Blanchard F., Lamy A., & Sabourin J.-C. (2021). A case of Pseudomyxoma Peritonei of an unexpected origin. Diagnostic pathology, 16(1), 119. https://doi.org/10.1186/s13000-021-01179-z
4. Moran B. J., & Cecil T. D. (2003). The etiology, clinical presentation, and management of pseudomyxoma peritonei. Surgical oncology clinics of North America, 12(3), 585-603. https://doi.org/10.1016/s1055-3207(03)00026-7
5. Mittal R., Chandramohan A., & Moran B. (2017). Pseudomyxoma peritonei: natural history and treatment. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 33(5), 511-519. https://doi.org/10.1080/02656736.2017.1310938
6. Esquivel J., & Sugarbaker P. H. (2000). Clinical presentation of the Pseudomyxoma peritonei syndrome. The British journal of surgery, 87(10), 1414-8. https://doi.org/10.1046/j.1365-2168.2000.01553.x
7. Carr N. J., Finch J., Ilesley I. C., Chandrakumaran K., Mohamed F., Mirnezami A., et al. (2012). Pathology and prognosis in pseudomyxoma peritonei: a review of 274 cases. Journal of clinical pathology, 65(10), 919-23. https://doi.org/10.1136/jclinpath-2012-200843
8. Khalifé M., Guigui P., Hoffmann E., & Ferrero E. (2020). Techniques d ’ ostéotomie vertébrale. 0(20), 1-19. https://doi.org/10.1016/S0246-0467(20)42625-X
9. Carr N. J., Cecil T. D., Mohamed F., Sobin L. H., Sugarbaker P. H., González-Moreno S., et al. (2016). A Consensus for Classification and Pathologic Reporting of Pseudomyxoma Peritonei and Associated Appendiceal Neoplasia: The Results of the Peritoneal Surface Oncology Group International (PSOGI) Modified Delphi Process. The American journal of surgical pathology, 40(1), 14-26. https://doi.org/10.1097/PAS.0000000000000535
10. Smeenk R. M., van Velthuysen M. L. F., Verwaal V. J., & Zoetmulder F. A. N. (2008). Appendiceal neoplasms and pseudomyxoma peritonei: a population based study. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 34(2), 196-201. https://doi.org/10.1016/j.ejso.2007.04.002
11. Belhamidi M. S., Zorkani Y., Krimou H., Kaoukabi A., Menfaa M., Sakit F., et al. (2019). [Pseudomyxoma peritonei (PMP) secondary to mucinous carcinoma of the ovary: a case study]. The Pan African medical journal, 33, 283. https://doi.org/10.11604/pamj.2019.33.283.17203
12. Ning S., Yang Y., Wang C., & Luo F. (2019). Pseudomyxoma peritonei induced by low-grade appendiceal mucinous neoplasm accompanied by rectal cancer: a case report and literature review. BMC surgery, 19(1), 42. https://doi.org/10.1186/s12893-019-0508-6
13. Prabhu R. M., Koshire S. R., & Khandelwal R. C. S. (2021). A Rare Case of Psoas Abscess Secondary to Mucinous Adenocarcinoma of the Appendix: A Case Report. Journal of orthopaedic case reports, 11(8), 1-5. https://doi.org/10.13107/jocr.2021.v11.i08.2340
14. Ghosh R. K., Somasundaram M., Ravakhah K., & Hassan C. (2016). Pseudomyxoma peritonei with intrathoracic extension: a rare disease with rarer presentation from low-grade mucinous adenocarcinoma of the appendix. BMJ case reports, 2016. https://doi.org/10.1136/bcr-2015-211076
15. Youssef H., Newman C., Chandrakumaran K., Mohamed F., Cecil T. D., & Moran B. J. (2011). Operative findings, early complications, and long-term survival in 456 patients with pseudomyxoma peritonei syndrome of appendiceal origin. Diseases of the colon and rectum, 54(3), 293-9. https://doi.org/10.1007/DCR.0b013e318202f026
16. McBride K., McFadden D., & Osler T. (2013). Improved survival of patients with pseudomyxoma peritonei receiving intraperitoneal chemotherapy with cytoreductive surgery: a systematic review and meta-analysis. The Journal of surgical research, 183(1), 246-52. https://doi.org/10.1016/j.jss.2012.12.040
17. Baratti D., Kusamura S., Guaglio M., Milione M., Pietrantonio F., Cavalleri T., et al. (2022). Relapse of Pseudomyxoma Peritonei After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: Pattern of Failure, Clinical Management and Outcomes. Annals of surgical oncology. https://doi.org/10.1245/s10434-022-12367-6
18. Proesmans V., Vandaele T., Van Slambrouck J., Wolthuis A., D Hoore A., Dekervel J., et al. (2022). Pleural decortication and hyperthermic intrathoracic chemotherapy for pseudomyxoma. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 39(1), 1153-1157. https://doi.org/10.1080/02656736.2022.2104938
19. Pestieau S. R., Esquivel J., & Sugarbaker P. H. (2000). Pleural extension of mucinous tumor in patients with pseudomyxoma peritonei syndrome. Annals of surgical oncology, 7(3), 199-203. https://doi.org/10.1007/BF02523654
20. Sugarbaker P. H., Chang D., & Stuart O. A. (2012). Hyperthermic intraoperative thoracoabdominal chemotherapy. Gastroenterology research and practice, 2012, 623417. https://doi.org/10.1155/2012/623417
21. Yahanda A. T., Buchowski J. M., & Wegner A. M. (2019). Treatment, complications, and outcomes of metastatic disease of the spine: from Patchell to PROMIS. Annals of translational medicine, 7(10), 216. https://doi.org/10.21037/atm.2019.04.83
22. Lau D., Deviren V., & Ames C. P. (2019). The impact of surgeon experience on perioperative complications and operative measures following thoracolumbar 3-column osteotomy for adult spinal deformity: overcoming the learning curve. Journal of neurosurgery. Spine, 32(2), 207-220. https://doi.org/10.3171/2019.7.SPINE19656
| Files | ||
| Issue | Vol 10 No 3 (2024) | |
| Section | Case Report | |
| DOI | https://doi.org/10.18502/jost.v10i3.16786 | |
| Keywords | ||
| Pseudomyxoma peritonei gelatinous disease thoracic spine vertebrectomy | ||
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How to Cite
1.
Huynh H, Lacroix M, Guigui P, Ferrero E, Meatchi T, KhaliféM. Pseudomyxoma peritonei lesion of the thoracic spine. J Orthop Spine Trauma. 2024;10(3):130-4.
