Simvastatin and Ezetimibe-Loaded Nanofibers Administered Locally to Augment Bone Healing
,
Abstract
No abstract is available.
References
1. Li D, Xia Y. Electrospinning of nanofibers: Reinventing the
wheel? Adv Mater. 2004;16(14):1151-71. doi:
10.1002/adma.200400719.
2. Weng L, Xie J. Smart electrospun nanofibers for controlled drug release: Recent advances and new perspectives. Curr Pharm Des. 2015;21(15):1944-59. doi: 10.2174/1381612821666150302151959. [PubMed: 25732665]. [PubMed Central: PMC5492677].
3. Torres-Martinez EJ, Cornejo Bravo JM, Serrano MA, Perez Gonzalez GL, Villarreal Gomez LJ. A Summary of electrospun nanofibers as drug delivery system: Drugs loaded and biopolymers used as matrices. Curr Drug Deliv. 2018;15(10):
1360-74. doi: 10.2174/1567201815666180723114326. [PubMed:
30033869]. [PubMed Central: PMC6376322].
4. Collignon AM, Lesieur J, Vacher C, Chaussain C, Rochefort GY. Strategies developed to induce, direct, and potentiate bone healing. Front Physiol. 2017;8:927. doi: 10.3389/fphys.2017.00927. [PubMed: 29184512]. [PubMed Central: PMC5694432].
5. Mills LA, Aitken SA, Simpson AHRW. The risk of non-union per fracture: Current myths and revised figures from a population of over 4 million adults. Acta Orthop. 2017;88(4):434-9. doi: 10.1080/17453674.2017.1321351. [PubMed: 28508682]. [PubMed Central: PMC5499337].
6. Kanakaris NK, Giannoudis PV. The health economics of the treatment of long-bone non-unions. Injury. 2007;38(Suppl 2): S77-S84. doi: 10.1016/s0020-1383(07)80012-x. [PubMed: 17920421].
7. Brinker MR, Hanus BD, Sen M, O'Connor DP. The devastating effects of tibial nonunion on health-related quality of life. J Bone Joint Surg Am. 2013;95(24):2170-6. doi: 10.2106/JBJS.L.00803. [PubMed: 24352770].
8. Morse LR, Coker J, Battaglino RA. Statins and bone health: A
mini review. Actual osteol. 2018;14(1):31-5. [PubMed: 30237809].
[PubMed Central: PMC6143288].
9. Wang Z, Li Y, Zhou F, Piao Z, Hao J. Effects of statins on bone mineral density and fracture risk: A PRISMA-compliant systematic review and meta-analysis. Medicine (Baltimore). 2016;95(22):e3042. doi: 10.1097/MD.0000000000003042. [PubMed: 27258488]. [PubMed Central: PMC4900696].
10. Lin TK, Chou P, Lin CH, Hung YJ, Jong GP. Long-term effect of statins on the risk of new-onset osteoporosis: A nationwide population-based cohort study. PLoS One. 2018;13(5):e0196713. doi: 10.1371/journal.pone.0196713. [PubMed: 29723231]. [PubMed Central: PMC5933736].
11. Piskin E, Isoglu IA, Bolgen N, Vargel I, Griffiths S, Cavusoglu T, et al. In vivo performance of simvastatin-loaded electrospun spiral-wound polycaprolactone scaffolds in reconstruction of cranial bone defects in the rat model. J Biomed Mater Res A. 2009;90(4):1137-51. doi: 10.1002/jbm.a.32157. [PubMed: 18671271].
12. Kalogirou M, Tsimihodimos V, Elisaf M. Pleiotropic effects of ezetimibe: do they really exist? Eur J Pharmacol. 2010;633 (1-3):62-70. doi: 10.1016/j.ejphar.2010.02.003. [PubMed: 20152830].
13. Berthold HK, Naini A, Di Mauro S, Hallikainen M, Gylling H, Krone W, et al. Effect of ezetimibe and/or simvastatin on coenzyme Q10 levels in plasma: A randomised trial. Drug Saf. 2006;29(8):703-12. doi: 10.2165/00002018-200629080-00007. [PubMed: 16872244].
14. Hajializade M, Moghtadaei M, Mirzaei A, Abdollahi Kordkandi S, Babaheidarian P, Pazoki-Toroudi H, et al. Significant effect of simvastatin and/or ezetimibe-loaded nanofibers on the healing of femoral defect: An experimental study. Mater Sci Eng C Mater Biol Appl. 2020;111:110861. doi: 10.1016/j.msec.2020.110861. [PubMed: 32279793].
1. Li D, Xia Y. Electrospinning of nanofibers: Reinventing the
wheel? Adv Mater. 2004;16(14):1151-71. doi:
10.1002/adma.200400719.
2. Weng L, Xie J. Smart electrospun nanofibers for controlled drug release: Recent advances and new perspectives. Curr Pharm Des. 2015;21(15):1944-59. doi: 10.2174/1381612821666150302151959. [PubMed: 25732665]. [PubMed Central: PMC5492677].
3. Torres-Martinez EJ, Cornejo Bravo JM, Serrano MA, Perez Gonzalez GL, Villarreal Gomez LJ. A Summary of electrospun nanofibers as drug delivery system: Drugs loaded and biopolymers used as matrices. Curr Drug Deliv. 2018;15(10):
1360-74. doi: 10.2174/1567201815666180723114326. [PubMed:
30033869]. [PubMed Central: PMC6376322].
4. Collignon AM, Lesieur J, Vacher C, Chaussain C, Rochefort GY. Strategies developed to induce, direct, and potentiate bone healing. Front Physiol. 2017;8:927. doi: 10.3389/fphys.2017.00927. [PubMed: 29184512]. [PubMed Central: PMC5694432].
5. Mills LA, Aitken SA, Simpson AHRW. The risk of non-union per fracture: Current myths and revised figures from a population of over 4 million adults. Acta Orthop. 2017;88(4):434-9. doi: 10.1080/17453674.2017.1321351. [PubMed: 28508682]. [PubMed Central: PMC5499337].
6. Kanakaris NK, Giannoudis PV. The health economics of the treatment of long-bone non-unions. Injury. 2007;38(Suppl 2): S77-S84. doi: 10.1016/s0020-1383(07)80012-x. [PubMed: 17920421].
7. Brinker MR, Hanus BD, Sen M, O'Connor DP. The devastating effects of tibial nonunion on health-related quality of life. J Bone Joint Surg Am. 2013;95(24):2170-6. doi: 10.2106/JBJS.L.00803. [PubMed: 24352770].
8. Morse LR, Coker J, Battaglino RA. Statins and bone health: A
mini review. Actual osteol. 2018;14(1):31-5. [PubMed: 30237809].
[PubMed Central: PMC6143288].
9. Wang Z, Li Y, Zhou F, Piao Z, Hao J. Effects of statins on bone mineral density and fracture risk: A PRISMA-compliant systematic review and meta-analysis. Medicine (Baltimore). 2016;95(22):e3042. doi: 10.1097/MD.0000000000003042. [PubMed: 27258488]. [PubMed Central: PMC4900696].
10. Lin TK, Chou P, Lin CH, Hung YJ, Jong GP. Long-term effect of statins on the risk of new-onset osteoporosis: A nationwide population-based cohort study. PLoS One. 2018;13(5):e0196713. doi: 10.1371/journal.pone.0196713. [PubMed: 29723231]. [PubMed Central: PMC5933736].
11. Piskin E, Isoglu IA, Bolgen N, Vargel I, Griffiths S, Cavusoglu T, et al. In vivo performance of simvastatin-loaded electrospun spiral-wound polycaprolactone scaffolds in reconstruction of cranial bone defects in the rat model. J Biomed Mater Res A. 2009;90(4):1137-51. doi: 10.1002/jbm.a.32157. [PubMed: 18671271].
12. Kalogirou M, Tsimihodimos V, Elisaf M. Pleiotropic effects of ezetimibe: do they really exist? Eur J Pharmacol. 2010;633 (1-3):62-70. doi: 10.1016/j.ejphar.2010.02.003. [PubMed: 20152830].
13. Berthold HK, Naini A, Di Mauro S, Hallikainen M, Gylling H, Krone W, et al. Effect of ezetimibe and/or simvastatin on coenzyme Q10 levels in plasma: A randomised trial. Drug Saf. 2006;29(8):703-12. doi: 10.2165/00002018-200629080-00007. [PubMed: 16872244].
14. Hajializade M, Moghtadaei M, Mirzaei A, Abdollahi Kordkandi S, Babaheidarian P, Pazoki-Toroudi H, et al. Significant effect of simvastatin and/or ezetimibe-loaded nanofibers on the healing of femoral defect: An experimental study. Mater Sci Eng C Mater Biol Appl. 2020;111:110861. doi: 10.1016/j.msec.2020.110861. [PubMed: 32279793].
| Files | ||
| Issue | Vol 6, No 3 (2020) | |
| Section | Commentary | |
| DOI | https://doi.org/10.18502/jost.v6i3.4972 | |
| Keywords | ||
| Bone Regeneration; Ezetimibe; Nanofibers; Simvastatin | ||
| Rights and permissions | |
|
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
How to Cite
1.
Amiri S, Yeganeh A, Moghtadaei M. Simvastatin and Ezetimibe-Loaded Nanofibers Administered Locally to Augment Bone Healing. J Orthop Spine Trauma. 2021;6(3):75-6.
